Antioxidant, antidiabetic, anti-inflammatory and anticancer potential of some seaweed extracts

This study aims to evaluate the secondary metabolites, cytotoxicity, antioxidant, antidiabetic, anti-inflammatory, and anticancer activities of four selected seaweeds Padina pavonica, Taonia atomaria, Jania rubens, Corallina elongata. The maximum value phenolic content (176.7 ± 6.9 mg gallic acid equivalents/g crude extract) tannin (26.5 4.3 tannic extract), was shown in methanol extract J. rubens P. respectively. While ethanol T. atomaria recorded highest values total flavonoid (374.1 ±27.4 quercetin saponins (30.2 0.7 cholesterol extract, respectively) compared other seaweeds. Methanol C. elongata exhibited greatest alkaloids (25.8 4.4 22.7 2.6 mg/g d wt.). pavonica established DPPH radical scavenging activity (55.7% 0.1) at 50 μg/mL. Among seaweed extracts, demonstrated α-amylase inhibition capacity (66.3% 0.0). species effectively prevented hypotonicity-induced haemolysis a concentration-dependent manner with diclofenac potassium as standard anti-inflammatory drug. In vitro, reported results also supported safety non-toxicity extracts on WI-38 cell line lower concentrations. growth HeLa Cancer Cell Lines drug Cisplatin.